EUVD-2026-12956
CVSS Vector
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N
Lifecycle Timeline
3Description
SAMtools is a program for reading, manipulating and writing bioinformatics file formats. The `mpileup` command outputs DNA sequences that have been aligned against a known reference. On each output line it writes the reference position, optionally the reference DNA base at that position (obtained from a separate file) and all of the DNA bases that aligned to that position. As the output is ordered by position, reference data that is no longer needed is discarded once it has been printed out. Under certain conditions the data could be discarded too early, leading to an attempt to read from a pointer to freed memory. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. This bug is fixed in versions 1.21.1 and 1.22. There is no workaround for this issue.
Analysis
SAMtools mpileup command contains a use-after-free vulnerability in reference data management that can leak sensitive program state information or trigger application crashes when processing aligned DNA sequences. The vulnerability affects versions prior to 1.2 and requires no authentication or user interaction to exploit, though a patch is not yet available. …
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Remediation
Within 30 days: Identify affected systems and apply vendor patches as part of regular patch cycle. Monitor vendor channels for patch availability.
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External POC / Exploit Code
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