Samtools

2 CVEs product

Monthly

CVE-2026-31973 MEDIUM This Month

SAMtools versions 1.17 and later contain a null pointer dereference vulnerability in the cram-size command due to missing error handling for the cram_decode_compression_header() function. When this function fails and returns an error, the code does not properly validate the return value before dereferencing the pointer, allowing an attacker to crash the application by providing a malformed CRAM file. This is a denial-of-service vulnerability with no active exploitation reported in the wild, though patches are available in versions 1.23.1, 1.22.2, and 1.21.1.

Denial Of Service Samtools
NVD GitHub VulDB
CVSS 4.0
6.9
EPSS
0.0%
CVE-2026-31972 MEDIUM This Month

SAMtools mpileup command contains a use-after-free vulnerability in reference data management that can leak sensitive program state information or trigger application crashes when processing aligned DNA sequences. The vulnerability affects versions prior to 1.2 and requires no authentication or user interaction to exploit, though a patch is not yet available. An attacker could leverage this to obtain information disclosure or cause denial of service against systems processing bioinformatics data with vulnerable SAMtools versions.

Use After Free Information Disclosure Denial Of Service Samtools
NVD GitHub VulDB
CVSS 4.0
6.9
EPSS
0.0%
CVE-2026-31973
EPSS 0% CVSS 6.9
MEDIUM This Month

SAMtools versions 1.17 and later contain a null pointer dereference vulnerability in the cram-size command due to missing error handling for the cram_decode_compression_header() function. When this function fails and returns an error, the code does not properly validate the return value before dereferencing the pointer, allowing an attacker to crash the application by providing a malformed CRAM file. This is a denial-of-service vulnerability with no active exploitation reported in the wild, though patches are available in versions 1.23.1, 1.22.2, and 1.21.1.

Denial Of Service Samtools
NVD GitHub VulDB
CVE-2026-31972
EPSS 0% CVSS 6.9
MEDIUM This Month

SAMtools mpileup command contains a use-after-free vulnerability in reference data management that can leak sensitive program state information or trigger application crashes when processing aligned DNA sequences. The vulnerability affects versions prior to 1.2 and requires no authentication or user interaction to exploit, though a patch is not yet available. An attacker could leverage this to obtain information disclosure or cause denial of service against systems processing bioinformatics data with vulnerable SAMtools versions.

Use After Free Information Disclosure Denial Of Service +1
NVD GitHub VulDB

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