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Samtools CVE-2026-31972

| EUVD-2026-12956 MEDIUM
Use After Free (CWE-416)
2026-03-18 GitHub_M
6.9
CVSS 4.0
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CVSS VectorNVD

CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N
Attack Vector
Network
Attack Complexity
Low
Privileges Required
None
User Interaction
None

Lifecycle Timeline

4
Patch available
Apr 16, 2026 - 05:29 EUVD
1.21.1
EUVD ID Assigned
Mar 18, 2026 - 21:00 euvd
EUVD-2026-12956
Analysis Generated
Mar 18, 2026 - 21:00 vuln.today
CVE Published
Mar 18, 2026 - 20:32 nvd
MEDIUM 6.9

DescriptionNVD

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. The mpileup command outputs DNA sequences that have been aligned against a known reference. On each output line it writes the reference position, optionally the reference DNA base at that position (obtained from a separate file) and all of the DNA bases that aligned to that position. As the output is ordered by position, reference data that is no longer needed is discarded once it has been printed out. Under certain conditions the data could be discarded too early, leading to an attempt to read from a pointer to freed memory. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. This bug is fixed in versions 1.21.1 and 1.22. There is no workaround for this issue.

AnalysisAI

SAMtools mpileup command contains a use-after-free vulnerability in reference data management that can leak sensitive program state information or trigger application crashes when processing aligned DNA sequences. The vulnerability affects versions prior to 1.2 and requires no authentication or user interaction to exploit, though a patch is not yet available. …

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RemediationAI

Within 30 days: Identify affected systems and apply vendor patches as part of regular patch cycle. Monitor vendor channels for patch availability.

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Vendor StatusVendor

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CVE-2026-31972 vulnerability details – vuln.today

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