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Bionemo Framework CVE-2026-24216

| EUVDEUVD-2026-31143 HIGH
Deserialization of Untrusted Data (CWE-502)
2026-05-20 nvidia GHSA-mfc6-w69g-6wj5
7.8
CVSS 3.1 · Vendor: nvidia
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Vulnerability Assessment

Weakness
CWE
OWASP Top 10:2025
A08:2025 - Software or Data Integrity Failures
ASVS 5.0
V1 - Encoding and Sanitization Safe deserialization, type allowlists
MITRE ATT&CK

2 techniques across 2 tactics: Execution, Initial Access

The technique list with ATT&CK links and the kill-chain view is part of the Basic plan and up.

This Week Schedule remediation this week. Why: HIGH severity (CVSS 7.0-8.9).
No patch listed yet 0.1% exploitation probability (EPSS)

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AnalysisAIv1 – May 20, 2026

Arbitrary code execution in NVIDIA BioNemo Framework on Linux allows a local attacker to abuse unsafe deserialization of untrusted data (CWE-502), leading to code execution, denial of service, information disclosure, and data tampering. The CVSS 7.8 vector indicates local attack vector with required user interaction, and no public exploit has been identified at time of analysis.

Affected VersionsENISA

BioNeMo Framework 0 <commit dfd83a7 in Main

Affects your stack

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Checking this CVE against your own stacks and servers is part of the Basic plan and up.

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  • Exploit and PoC references, threat intelligence from 22 sources

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Severity by source

Vendor (nvidia) PRIMARY 7.8 HIGH
AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

Primary rating from Vendor (nvidia) · only source for this CVE.

CVSS VectorVendor: nvidia

Attack Vector
Local
Attack Complexity
Low
Privileges Required
None
User Interaction
Required
Scope
Unchanged
Confidentiality
High
Integrity
High
Availability
High

DescriptionCVE.org

NVIDIA BioNemo for Linux contains a vulnerability where a user could cause a deserialization of untrusted data. A successful exploit of this vulnerability might lead to code execution, denial of service, information disclosure, and data tampering.

Executive ViewAI

Why It Matters

NVIDIA BioNemo Framework on Linux contains a HIGH-severity arbitrary code execution vulnerability (CVE-2026-24216) through unsafe deserialization, exploitable by local attackers during normal use-threatening data integrity, system availability, and system confidentiality across affected organizations. No public exploit is identified at time of analysis. With no vendor patch currently available, immediate compensating controls and deployment assessment are required.

Recommended Action

Within 24 hours: Inventory all systems running NVIDIA BioNemo Framework; restrict local user access and apply OS-level least-privilege controls (dedicate to a service account with minimal permissions). Within 7 days: Enable security event logging and alerting for unexpected process execution and file access from BioNemo processes; audit local user access logs over the past 30 days. Within 30 days: Contact NVIDIA for patch availability timeline and ETA; evaluate whether BioNemo can be disabled if not actively required; assess feasibility of isolated or air-gapped deployment if continued operation is necessary.

Business Impact: High
Compensating Controls

Restrict local user access to BioNemo systems through OS access controls; run BioNemo under a dedicated service account with minimal file system and process permissions; enable comprehensive security event logging and alerting for process execution and file access anomalies; consider operational isolation of affected systems from general-use networks until a vendor patch becomes available.

Threat Intelligence Overview

EPSS Score
0.1%
Top 83% exploitable
Data Quality
5 sources
Confidence: Medium

How this decision was reached

The engine reads each signal below and applies a fixed list of rules from top to bottom. The first rule that matches sets the recommended action – like a statement, every line is shown.

SignalValue
Severity HIGH
CISA KEV No
Public POC No
EPSS 0.1%
Patch available No
Active threat No
Deciding rule
HIGH severity (CVSS 7.0-8.9)
What every action level means
Emergency Immediate action required. Criteria: CRITICAL + in CISA KEV (actively exploited) without patch, OR CRITICAL + EPSS > 30% without patch, OR CRITICAL + active threat signals without patch.
Act Now Prioritize within 24-48h. Criteria: in KEV with patch available, OR CRITICAL + public POC, OR HIGH + EPSS > 10%, OR CRITICAL + active threat, OR any CRITICAL severity.
This Week Schedule remediation this week. Criteria: HIGH severity (CVSS 7.0-8.9). Patch within normal change window.
This Month Plan within 30 days. Criteria: MEDIUM severity (CVSS 4.0-6.9), lower exploitation probability. Include in regular patch cycle.
Monitor Track and reassess. Criteria: LOW severity (CVSS 0.1-3.9), minimal exploitation risk. No immediate action needed.

SSVC AssessmentENISA

SSVC Decision
Scheduled
Exploitation
None
System Exposure· derived
Small
Automatable
No
Human Impact
High
Technical Impact
Total

Priority Score

39
Low Medium High Critical
KEV: 0
EPSS: 0
CVSS: +39
PoC: 0
Weaponized: 0
Threat intel: 0
Gov advisory: 0

Attack Technique

Insecure deserialization occurs when an application converts serialized data (a stream of bytes representing an object's state) back into a living object without proper validation.

Information disclosure occurs when an application unintentionally exposes sensitive data that aids attackers in reconnaissance or directly compromises security.

Remote Code Execution represents the critical moment when an attacker successfully runs arbitrary code on a target system without physical access.

Denial of Service attacks render applications or systems unavailable by overwhelming resources or triggering failure conditions.

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