Severity by source
AV:N/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Primary rating from NVD · only source for this CVE.
CVSS VectorNVD
CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
Lifecycle Timeline
3DescriptionCVE.org
NVIDIA BioNeMo contains a vulnerability where a user could cause a deserialization of untrusted data. A successful exploit of this vulnerability might lead to code execution, denial of service, information disclosure, and data tampering.
AnalysisAI
Insecure deserialization in NVIDIA BioNeMo Framework enables remote code execution when attackers can induce users to process malicious serialized data. This vulnerability (CWE-502) affects the BioNeMo Framework with network-reachable attack surface (AV:N) and low complexity (AC:L), requiring only user interaction (UI:R) but no authentication (PR:N). The CVSS 8.8 rating reflects critical impacts across confidentiality, integrity, and availability. No public exploit identified at time of analysis, though the deserialization vulnerability class is well-understood and commonly exploited. EPSS data not available for this CVE.
Technical ContextAI
NVIDIA BioNeMo Framework is a computational biology platform for AI-driven drug discovery and molecular simulation. The vulnerability stems from CWE-502 (Deserialization of Untrusted Data), a dangerous code pattern where applications deserialize data from untrusted sources without sufficient validation. In Python-based frameworks like BioNeMo, this commonly involves pickle, PyYAML, or similar serialization libraries that can instantiate arbitrary objects during deserialization. When user-controllable data flows into deserialization functions, attackers can craft malicious payloads containing executable code or object chains that trigger upon reconstruction. The CPE identifier (cpe:2.3:a:nvidia:bionemo_framework:*:*:*:*:*:*:*:*) indicates all versions of the framework are potentially affected, though specific version ranges require vendor advisory confirmation.
RemediationAI
Consult NVIDIA security advisory 5808 at https://nvidia.custhelp.com/app/answers/detail/a_id/5808 for official remediation guidance and patched BioNeMo Framework versions. Primary mitigation involves upgrading to the vendor-specified secure release that implements input validation and restricted deserialization mechanisms. Interim risk reduction measures include restricting BioNeMo Framework access to trusted users only, implementing network segmentation to limit framework exposure, validating and sandboxing all external data sources before processing, disabling automatic deserialization of user-supplied files, and monitoring for suspicious model loading or configuration parsing activities. Organizations unable to immediately patch should enforce strict data provenance controls and prohibit processing of untrusted serialized objects until updates are deployed.
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Same weakness CWE-502 – Deserialization of Untrusted Data
View allSame technique Deserialization
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External POC / Exploit Code
Leaving vuln.today
EUVD-2026-17516