CVSS Vector
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:P/VC:N/VI:H/VA:L/SC:N/SI:N/SA:N
Lifecycle Timeline
4Description
HTSlib is a library for reading and writing bioinformatics file formats. GZI files are used to index block-compressed GZIP [BGZF] files. In the GZI loading function, `bgzf_index_load_hfile()`, it was possible to trigger an integer overflow, leading to an under- or zero-sized buffer being allocated to store the index. Sixteen zero bytes would then be written to this buffer, and, depending on the result of the overflow the rest of the file may also be loaded into the buffer as well. If the function did attempt to load the data, it would eventually fail due to not reading the expected number of records, and then try to free the overflowed heap buffer. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. The easiest work-around is to discard any `.gzi` index files from untrusted sources, and use the `bgzip -r` option to recreate them.
Analysis
HTSlib versions prior to 1.23.1, 1.22.2, and 1.21.1 contain a heap buffer overflow vulnerability in the GZI index loading function `bgzf_index_load_hfile()`. An integer overflow during buffer allocation allows attackers to craft malicious `.gzi` files that trigger heap memory corruption, potentially leading to denial of service, data corruption, or remote code execution when a user opens the compromised file. …
Sign in for full analysis, threat intelligence, and remediation guidance.
Remediation
Within 7 days: Identify all affected systems and apply vendor patches promptly. If patching is delayed, consider network segmentation to limit exposure.
Sign in for detailed remediation steps.
Priority Score
Vendor Status
Debian
| Release | Status | Fixed Version | Urgency |
|---|---|---|---|
| bullseye | vulnerable | 1.11-4 | - |
| bookworm | vulnerable | 1.16+ds-3 | - |
| trixie | vulnerable | 1.21+ds-1 | - |
| forky, sid | vulnerable | 1.22.1+ds2-1 | - |
| (unstable) | fixed | (unfixed) | - |
Share
External POC / Exploit Code
Leaving vuln.today
EUVD-2026-12946