Skip to main content

Python EUVDEUVD-2022-49099

| CVE-2022-46280 HIGH
Access of Uninitialized Pointer (CWE-824)
2026-07-01 https://github.com/openbabel/openbabel GHSA-7rcm-w6ff-j43w GHSA-8qxc-57hf-hc9j
7.8
CVSS 3.1 · GitHub Advisory
View

Vulnerability Assessment

Weakness
CWE
ASVS 5.0
V15 - Secure Coding and Architecture Uninitialized pointer prevention
MITRE ATT&CK

1 technique across 1 tactic: Execution

The technique list with ATT&CK links and the kill-chain view is part of the Basic plan and up.

Impact

CVSS score of 7.8 (HIGH). Attack characteristics: local attack vector, low complexity, no privileges required, user interaction required. EPSS exploitation probability: 0.84%.

Exploit ScenarioDerived

Successful exploitation could compromise the high-severity affected system.

This Week Schedule remediation this week. Why: HIGH severity (CVSS 7.0-8.9).
Patch available 0.8% exploitation probability (EPSS)

Get an e-mail when this CVE is exploited, patched or re-scored. Free account.

Alert me

AnalysisAI

Summary A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file. Rated high severity (CVSS 7.8), this vulnerability is no authentication required, low attack complexity.

RemediationAI

A vendor patch is available. Apply the latest security update as soon as possible. Apply vendor patches when available. Implement network segmentation and monitoring as interim mitigations.

Affected VersionsENISA

Open Babel 3.1.1
Open Babel master commit 530dbfa3

Affected Packages

pypi openbabel fix: 3.2.0
euvd open_babel no fix

Source: OSV (Open Source Vulnerabilities)

Affects your stack

Affects 2 packages in pypi, euvd

Checking this CVE against your own stacks and servers is part of the Basic plan and up.

Technical ContextAI · show details

This vulnerability is classified under CWE-824.

Summary A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file.

Details The flaw was in the pFormat handling of the PQS reader. A malformed input caused the parser to dereference a format pointer that had never been initialized.

Impact Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions All releases up to and including 3.1.1.

Patched version 3.2.0 (released 2026-05-26).

Patch Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit Reported by Cisco TALOS. Version information: version

3.2.0.

Know when Python gets its next vulnerability

  • Watch products and get an email when something new is published
  • Check this CVE against your own stack and servers
  • Exploit and PoC references, threat intelligence from 22 sources

No credit card · 7-day full trial

Severity by source

GitHub Advisory PRIMARY 7.8 HIGH
AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
SUSE CRITICAL

Primary rating from GitHub Advisory.

CVSS VectorGitHub Advisory

Attack Vector
Local
Attack Complexity
Low
Privileges Required
None
User Interaction
Required
Scope
Unchanged
Confidentiality
High
Integrity
High
Availability
High

DescriptionGitHub Advisory

Summary

A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file.

Details

The flaw was in the pFormat handling of the PQS reader. A malformed input caused the parser to dereference a format pointer that had never been initialized.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported by Cisco TALOS.

Threat Intelligence Overview

EPSS Score
0.8%
Top 47% exploitable
Threat Intel
1
1 source
Data Quality
7 sources
Confidence: High
EUVD NVD CVE.org EPSS Vulnrichment GHSA Vendor GitHub

How this decision was reached

The engine reads each signal below and applies a fixed list of rules from top to bottom. The first rule that matches sets the recommended action – like a statement, every line is shown.

SignalValue
Severity HIGH
CISA KEV No
Public POC No
EPSS 0.8%
Patch available Yes
Active threat No
Deciding rule
HIGH severity (CVSS 7.0-8.9)
What every action level means
Emergency Immediate action required. Criteria: CRITICAL + in CISA KEV (actively exploited) without patch, OR CRITICAL + EPSS > 30% without patch, OR CRITICAL + active threat signals without patch.
Act Now Prioritize within 24-48h. Criteria: in KEV with patch available, OR CRITICAL + public POC, OR HIGH + EPSS > 10%, OR CRITICAL + active threat, OR any CRITICAL severity.
This Week Schedule remediation this week. Criteria: HIGH severity (CVSS 7.0-8.9). Patch within normal change window.
This Month Plan within 30 days. Criteria: MEDIUM severity (CVSS 4.0-6.9), lower exploitation probability. Include in regular patch cycle.
Monitor Track and reassess. Criteria: LOW severity (CVSS 0.1-3.9), minimal exploitation risk. No immediate action needed.

SSVC AssessmentENISA

SSVC Decision· derived
Scheduled
Exploitation
None
System Exposure· derived
Small
Automatable
Yes
Human Impact· derived
Medium
Technical Impact
Total

Priority Score

40
Low Medium High Critical
KEV: 0
EPSS: +1
CVSS: +39
PoC: 0
Weaponized: 0
Threat intel: 0
Gov advisory: 0

Attack Technique

Memory corruption occurs when a program writes data beyond the boundaries of allocated memory regions or accesses memory in unintended ways, violating the integrity of the process's address space.

Information disclosure occurs when an application unintentionally exposes sensitive data that aids attackers in reconnaissance or directly compromises security.

More in Python

View all
CVE-2025-24016 CRITICAL POC
9.9 Feb 10

Wazuh SIEM platform versions 4.4.0 through 4.9.0 contain an unsafe deserialization vulnerability in the DistributedAPI t

CVE-2025-27520 CRITICAL POC
9.8 Apr 04

BentoML version 1.4.2 and earlier contains an unauthenticated remote code execution vulnerability through insecure deser

CVE-2025-2945 CRITICAL POC
9.9 Apr 03

pgAdmin 4 contains critical remote code execution vulnerabilities in the Query Tool download and Cloud Deployment endpoi

CVE-2013-5093 MEDIUM POC
6.8 Sep 27

The renderLocalView function in render/views.py in graphite-web in Graphite 0.9.5 through 0.9.10 uses the pickle Python

CVE-2025-32375 CRITICAL POC
9.8 Apr 09

BentoML is a Python library for building online serving systems optimized for AI apps and model inference. Rated critica

CVE-2014-0224 HIGH POC
7.4 Jun 05

OpenSSL before 0.9.8za, 1.0.0 before 1.0.0m, and 1.0.1 before 1.0.1h does not properly restrict processing of ChangeCiph

CVE-2024-21644 HIGH POC
7.5 Jan 08

pyLoad download manager version prior to 0.5.0b3.dev77 exposes the Flask SECRET_KEY through an unauthenticated endpoint.

CVE-2026-33017 CRITICAL POC
9.3 Mar 17

Langflow (a visual LLM pipeline builder) contains a critical unauthenticated code execution vulnerability (CVE-2026-3301

CVE-2017-9462 HIGH POC
8.8 Jun 06

In Mercurial before 4.1.3, "hg serve --stdio" allows remote authenticated users to launch the Python debugger, and conse

CVE-2026-49869 CRITICAL POC
10.0 Jun 26

Unauthenticated remote code execution affects Kestra OSS (the open-source event-driven orchestration platform) prior to

CVE-2026-39987 CRITICAL POC
9.3 Apr 08

Unauthenticated remote code execution in Marimo ≤0.20.4 allows attackers to execute arbitrary system commands via the `/

CVE-2024-21645 MEDIUM POC
5.3 Jan 08

pyLoad is the free and open-source Download Manager written in pure Python. Rated medium severity (CVSS 5.3), this vulne

Vendor StatusVendor

SUSE

Severity: Critical
Product Status
openSUSE Tumbleweed Fixed

This site uses cookies essential for authentication and security. No tracking or analytics cookies are used. Privacy Policy