What is the CVSS score of CVE-2022-46280?

CVE-2022-46280 has a CVSS 3.1 base score of 7.8 (High). CVSS vector: CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H. EPSS exploitation probability: 0.8%.

Is there a patch available for CVE-2022-46280?

Yes, a patch is available for CVE-2022-46280. Update the affected software to the latest version immediately.

Python CVE-2022-46280

EUVD-2022-49099 HIGH

Access of Uninitialized Pointer (CWE-824)

2026-07-01 https://github.com/openbabel/openbabel

GHSA-7rcm-w6ff-j43w

GHSA-8qxc-57hf-hc9j

Python Cisco Information Disclosure Memory Corruption Suse

7.8

CVSS 3.1 · GitHub Advisory

Severity by source

GitHub Advisory PRIMARY

7.8 HIGH

AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

SUSE

CRITICAL

qualitative

Primary rating from GitHub Advisory.

CVSS VectorGitHub Advisory

CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

Attack Vector

Local

Attack Complexity

Low

Privileges Required

None

User Interaction

Required

Scope

Unchanged

Confidentiality

High

Integrity

High

Availability

High

Lifecycle Timeline

CVE Published

Jul 01, 2026 - 17:48 github-advisory

HIGH 7.8

Blast Radius

ecosystem impact

† from your stack dependencies † transitive graph · vuln.today resolves 4-path depth

27 pypi packages depend on openbabel (25 direct, 2 indirect)

Ecosystem-wide dependent count for version 3.2.0.

DescriptionGitHub Advisory

Summary

A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file.

Details

The flaw was in the pFormat handling of the PQS reader. A malformed input caused the parser to dereference a format pointer that had never been initialized.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported by Cisco TALOS.

AnalysisAI

Summary A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file. Rated high severity (CVSS 7.8), this vulnerability is no authentication required, low attack complexity.

Technical ContextAI

This vulnerability is classified under CWE-824.

Summary A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file.

Details The flaw was in the `pFormat` handling of the PQS reader. A malformed input caused the parser to dereference a format pointer that had never been initialized.

Impact Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the `obabel` tool, the `OBConversion` API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions All releases up to and including 3.1.1.

Patched version 3.2.0 (released 2026-05-26).

Patch Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda A minimized reproducer for this CVE is checked in under `test/files/fuzz_regress/` and is exercised on every CI build under ASAN+UBSAN by the `fuzzregresstest` harness.

Credit Reported by Cisco TALOS. Version information: version

3.2.0.

RemediationAI

A vendor patch is available. Apply the latest security update as soon as possible. Apply vendor patches when available. Implement network segmentation and monitoring as interim mitigations.

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Vendor StatusVendor

SUSE

Severity: Critical

Product	Status
openSUSE Tumbleweed	Fixed

CVE-2022-46280 vulnerability details – vuln.today

Back

Python CVE-2022-46280

Severity by source

CVSS VectorGitHub Advisory

Lifecycle Timeline

Blast Radius

DescriptionGitHub Advisory

Summary

Details

Impact

Affected versions

Patched version

Patch

Credit

AnalysisAI

Summary A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file. Rated high severity (CVSS 7.8), this vulnerability is no authentication required, low attack complexity.

Technical ContextAI

Summary A memory-safety vulnerability in Open Babel's PQS parser caused an uninitialized pointer dereference when reading a crafted input file.

Details The flaw was in the pFormat handling of the PQS reader. A malformed input caused the parser to dereference a format pointer that had never been initialized.

Affected versions All releases up to and including 3.1.1.

Patched version 3.2.0 (released 2026-05-26).

Patch Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit Reported by Cisco TALOS. Version information: version

RemediationAI

More in Python

Same weakness CWE-824 – Access of Uninitialized Pointer

Same technique Information Disclosure

Vendor StatusVendor

SUSE

Share

External POC / Exploit Code

Details The flaw was in the `pFormat` handling of the PQS reader. A malformed input caused the parser to dereference a format pointer that had never been initialized.

Patch Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda A minimized reproducer for this CVE is checked in under `test/files/fuzz_regress/` and is exercised on every CI build under ASAN+UBSAN by the `fuzzregresstest` harness.