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MONAI CVE-2026-100845

| EUVDEUVD-2026-87843 HIGH
Deserialization of Untrusted Data (CWE-502)
2026-09-27 VulnCheck GHSA-4jj3-3266-2688
8.5
CVSS 4.0 · Vendor: VulnCheck
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Severity by source

Vendor (VulnCheck) PRIMARY
8.5 HIGH
CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
vuln.today AI
7.8 HIGH

Attacker supplies a malicious file the victim must load (AV:L, UI:R), no privileges or special complexity needed, and pickle execution yields full code execution in the victim context (C/I/A:H).

3.1 AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
4.0 AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N

Primary rating from Vendor (VulnCheck).

CVSS VectorVendor: VulnCheck

Attack Vector
Local
Attack Complexity
Low
Privileges Required
None
User Interaction
P
Scope
X

Lifecycle Timeline

5
POC Analysis Generated
Sep 27, 2026 - 11:23 vuln.today
Patch available
Sep 27, 2026 - 03:16 EUVD
Metadata Corrected
Sep 27, 2026 - 02:40 vuln.today
tag: Python added
Analysis Generated
Sep 27, 2026 - 02:24 vuln.today
CVE Published
Sep 27, 2026 - 01:28 cve.org
HIGH 8.5

DescriptionCVE.org

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

AnalysisAI

Arbitrary code execution in MONAI versions prior to 1.6.0 occurs when a crafted .npy or .npz file is loaded through the NumpyReader class, which hardcodes numpy.load with allow_pickle=True. An unauthenticated attacker who can place a malicious file on a path the victim opens can trigger pickle deserialization, leading to full compromise of confidentiality, integrity, and availability. …

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Attack ChainAIDerived

Hypothetical attack flow derived from CVE metadata

Access
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Delivery
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Exploit
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Execution
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Impact
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Vulnerability AssessmentAI

Exploitation Exploitation requires a victim to load an attacker-supplied .npy or .npz file through MONAI's standard data pipeline (LoadImage transform or any dataset class such as PersistentDataset/CacheDataset/SmartCacheDataset, which auto-select NumpyReader for those extensions). … Additional conditions and limiting factors are described in the full assessment.
Risk Assessment This is a genuine remote-code-execution-class deserialization flaw (CWE-502), but the exploitation model is local/interaction-dependent rather than remotely wormable. … Full risk analysis with EPSS, KEV, and SSVC signal comparison available after sign-in.
Exploit Scenario Full exploit scenario with step-by-step reproduction available after sign-in.
Remediation Vendor-released patch: 1.6.0. … Detailed patch versions, workarounds, and compensating controls in full report.

Recommended ActionAI

Within 24 hours, identify all systems running MONAI versions prior to 1.6.0, inventory any pipelines that use NumpyReader or load .npy/.npz files, and instruct users not to open untrusted array or model files; where possible, disable NumpyReader or enforce numpy.load(..., allow_pickle=False) in custom wrappers. …

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CVE-2026-100845 vulnerability details – vuln.today

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