Which versions of OpenClinica Community Edition are affected by CVE-2025-12922?

Organizations using OpenClinica Community Edition should be aware of moderate risk from CVE-2025-12922, a path traversal vulnerability rated CVSS 5.3. This could allow unauthorized file access.

How to fix or mitigate CVE-2025-12922?

Within 30 days: Identify affected systems running OpenClinica Community Edition and apply vendor patches as part of regular patch cycle. Review file handling controls.

OpenClinica Community Edition CVE-2025-12922

Q: What is the CVSS score of CVE-2025-12922?

CVE-2025-12922 has a CVSS 4.0 base score of 2.1 (Low). CVSS vector: CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:L/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X. EPSS exploitation probability: 0.1%.

LOW

Path Traversal (CWE-22)

2025-11-10 cna@vuldb.com

Path Traversal

2.1

CVSS 4.0 · NVD

Severity by source

NVD PRIMARY

2.1 LOW

CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:L/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X

Primary rating from NVD · only source for this CVE.

CVSS VectorNVD

CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:L/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X

Attack Vector

Network

Attack Complexity

Low

Privileges Required

Low

User Interaction

None

Scope

Lifecycle Timeline

Severity Changed

Apr 29, 2026 - 01:11 NVD

MEDIUM LOW

CVSS changed

Apr 29, 2026 - 01:11 NVD

5.3 (MEDIUM) 2.1 (LOW)

Analysis Generated

Mar 28, 2026 - 19:21 vuln.today

CVE Published

Nov 10, 2025 - 01:15 nvd

MEDIUM 5.3

DescriptionCVE.org

A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way.

AnalysisAI

A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. Rated medium severity (CVSS 5.3), this vulnerability is remotely exploitable, low attack complexity. No vendor patch available.

Technical ContextAI

This vulnerability is classified as Path Traversal (CWE-22), which allows attackers to access files and directories outside the intended path. A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way. Affected products include: Openclinica. Version information: up to 3.12.2.

RemediationAI

No vendor patch is available at time of analysis. Monitor vendor advisories for updates. Validate and canonicalize file paths. Use chroot or sandboxing. Reject input containing path separators or '../' sequences.